Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway

Bone marrow-derived mesenchymal cells (BM-MSCs) are able to differentiate into adipocytes, which can secrete adipokines to affect BM-MSC proliferation and differentiation.Recent evidences indicated that adipocytes can secrete fatty acid metabolites, such as palmitic acid methyl ester (PAME), which is able to cause vasorelaxation and exerts anti-inf

read more



Extracellular vesicles of minimalistic Mollicutes as mediators of immune modulation and horizontal gene transfer

Abstract Extracellular vesicles (EVs) are central components of bacterial secretomes, including the small, cell wall-less Mollicutes.Although EV release in Mollicutes has been reported, EV proteomic composition and function have not been explored yet.We developed a protocol for isolating EVs of the pathogens Mycoplasma mycoides subsp.capri (Mmc) an

read more